Approaches to Manage Postoperative Pain Following Total Knee Arthroplasty

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Approaches to Manage Postoperative Pain Following Total Knee Arthroplasty

The investigators, Department of Orthopaedic Surgery, Cleveland Clinic, Ohio found out that a periarticular injection of liposomal bupivacaine with an adductor canal block (LB+ACB) exhibited an equal efficacy for postoperative TKA pain control as the femoral nerve block (FNB). The TKA presented postoperative pain, which needs to be appropriately managed.

This study focused on evaluating the proper regimen to manage this postoperative pain.

The retrospective analysis of the 557 consecutive primary TKA cases was conducted at a single hospital from 2010 to 2014. Out of 557 cases, only 390 remained after matching the enrollment criteria. A comparison was done between Inpatient and post-discharge variables linked to pain, cost, narcotic use, and healthcare resource utilisation.

No significant differences were observed in the demographics between the two groups. The patients of the FNB group utilised fewer narcotics overall than LB+ACB group. But, the LB+ACB group presented with fewer opioid-associated adverse events along with fewer readmissions and operations, lower costs and shorter length of stay. Both approaches provide relief from pain during the analysis, but for some of the subjects, LB+ACB is not the first option.


Surg Technol Int. 

Link to the source:

Original title of the article:

A Comparison of Pain Management Protocols Following Total Knee Arthroplasty: Femoral Nerve Block versus Periarticular Injection of Liposomal Bupivacaine with an Adductor Canal Block.


Sandhu S et al.

Therapeutic, Bupivacaine, Pain, Local Anesthesia, Efficacy, Safety
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