Clinical Research

Clinical Research
Key Take-Away:

Thiazide diuretic may decrease the risk of fracture, indicating the protective effect of this class in clinical practice.

Osteoporosis is a major chronic condition worldwide, and the major health issue in the USA especially in the aging population. About 300,000 people aged 65 and older are hospitalized each year due to hip fracture, a situation which often leads to decreased quality of life.

Osteoporosis Int. 2018 Mar 25
20min read    
Clinical Research
Key Take-Away:

In middle-aged people with mild radiographic osteoarthritis (OA), structural features changes do occur  a little over a year, irrespective of weight patients loss status.

Osteoarthritis (OA) is a principal cause of disability and a more massive public health problem in the United States.

Osteoarthritis and Cartilage
20min read    
Clinical Research
Key Take-Away:

Home-based, telephone-delivered Cognitive-Behavioral Therapy (CBT) and Supportive Care (SC) treatments did not significantly differ in their benefits for back pain severity and disability, and may warrant further research for applications to hospital settings.

Over the past decade, there is a drastically hype in the prevalence of chronic back pain (CBP) in the US population, advising a need for more treatment resources.

The Clinical Journal of Pain 2018;34(4): 322–327
22min read    
Clinical Research
Key Take-Away:

Reliable predictive determinants that can distinguish patients who could best benefit from intra-articular hyaluronic acid (IAHA) treatment include severe knee pain, younger age, and less severe structural damage. These could be implemented in clinical practice as a useful guide for physicians to plan the treatment.

Knee osteoarthritis (OA) is a chronic inflammatory disorder. Various types of treatments are recommended nowadays that primarily focus on two strategies: 1) achieving relief from the symptoms and 2) significant improvement in the body functions. 

Arthritis Res Ther. 2018 Mar 1;20(1):40.
19min read    
Clinical Research
Key Take-Away:

Individuals hospitalized for a head injury are more likely to have new onset and worsening of pre-existing headache and persistent headache, compared to general population. This supports the entity of the ICHD-3 beta diagnosis “persistent headache attributed to traumatic injury to the head”.

For the global society, headache puts a major impact on the lives of individuals. The number of studies reported headache as a major cause of morbidity. After any head injury, headache is the most frequent symptom. 

J Headache Pain. 2018 Jan 22;19(1):8.
22min read