Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses. Sinusitis is the fifth most common diagnosis in the world; more than 1 in 5 antibiotics prescribed in adults are for sinusitis. Irrespective of the high incidence and economic burden of sinusitis, significant practice dissimilarities exist through and within the numerous disciplines involved in managing the condition. The guideline is applicable for patients aged 18 years and above with a clinical diagnosis of uncomplicated rhinosinusitis.
- Rhinosinusitis is defined as a symptomatic inflammation of the paranasal sinuses and the nasal cavity. The term rhinosinusitis is preferred because sinusitis is almost always accompanied by inflammation of the contiguous nasal mucosa. Therefore, rhinosinusitis is used in throughout the guideline.
- Uncomplicated rhinosinusitis is defined as rhinosinusitis without clinically evident extension of inflammation outside the paranasal sinuses and nasal cavity at the time of diagnosis (e.g., no neurologic, ophthalmologic, or soft tissue involvement).