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August 19, 2017

Crescendo Bioscience, a wholly-owned subsidiary of Myriad Genetics, Inc., put forward the new data on the use of Vectra® Disease Activity (DA) test to predict treatment response in patients suffering from rheumatoid arthritis (RA). The report was published online in the journal Arthritis & Rheumatology.

Globe NewsWire
9min read    
August 19, 2017

Two spine-related studies have been recognised as the research highlights for 2016 by US National Institutes of Health (NIH). Research into the effects of meditation and cognitive behavioural therapy on low back pain has been regarded as “Clinical Breakthrough”, while a study investigating the ability of electrical epidural stimulation to help move the hands of paralysed individuals was regarded as“Promising Medical Advance”.

NIH
14min read    
August 19, 2017

The US Food and Drug Administration (USFDA) approved the first-ever drug Nusinersen for spinal muscular atrophy (SMA) to treat children and adults. Spinal muscular atrophy is a devastating neurodegenerative disorder and genetic disease that causes muscle weakness and progressive loss of movement. This disease attacks nerve cells, called motor neurons, in the spinal cord, thereby weakening the muscles. Ultimately, this affects walking, crawling, breathing, swallowing, and control over head and the neck. Spinraza is approved for use across the range of spinal muscular atrophy patients.

FDA
11min read    
August 19, 2017

Gout is one of the most painful forms of arthritis, characterized by recurrent attacks of a red, tender, hot, and swollen joint. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or urate nephropathy. It occurs due to elevated levels of uric acid in the blood.

Annals of Internal Medicine
8min read    
August 19, 2017

The Food and Drug Administration (FDA) has recently approved "Onzetra Xsail", a low-dose sumatriptan powder delivered intranasally for the treatment of migraine with or without aura, in adult patients. Onzetra is a nasal powder, but it is not sprayed or inhaled through the nostrils. It uses the Xsail breath-powered delivery device, which delivers a low dose into the nose.

FDA
9min read    
Key Take-Away:

 A 800 mg/day pharmaceutical-grade Chondroitin sulphate was found to be better than placebo and similar to celecoxib in alleviating pain and enhancing function in patients with symptomatic knee osteoarthritis (OA) over 6 months.

Osteoarthritis is one of the most common musculoskeletal disorders that significantly impact the quality of life of people suffering from it.  It is known to be a chief cause of pain, loss of funct

Ann Rheum Dis 2017; 0:1–7.
24min read    

Medication-overuse headache (MOH) is a debilitating condition in which frequent and prolonged use of medication for the acute treatment of pain results in the worsening of the headache. According to the International Classification of Headache Disorders, 3rd Edition, Beta (ICHD-3,''MOH is defined as the headache occurring on 15 or more days per month developing as a consequence of regular overuse of acute or symptomatic headache medication (on 10 or more, or 15 or more days per month, depending on the medication) for more than 3 months''. Prevalence is often reported as 1–2% but can be as high as 7% overall, with higher proportions among women and in those with a low socioeconomic position. It is not as prevalent as tension type headache or migraine but it is very disabling. The pathophysiology is complex and not completely known. It involves genetic and behavioral factors.

13min read    

Dysmenorrhea, a painful menstruation, is a common gynecological condition which usually affects the women in the reproductive years. Menstrual cramps can occur a few days prior to the menstruation or even during the menstruation. Dysmenorrhea is further classified into 2 subcategories based on the history and the examination:

  • Primary dysmenorrhea which occurs in the absence of pelvic pathology
  • Secondary dysmenorrhea which occurs in the presence of pelvic pathology
12min read    

Occurrence of headache is very common nowadays, even in kids. Parents usually consider these headaches as a severe problem in kids. Physical examination by doctor is preferred, that help decide whether neuro-imaging is required or not. Mostly, based on the diagnostic reports, treatment of headache is initiated. 

16min read    

Ankylosing spondylitis (AS) is a chronic immune-mediated inflammatory disease with worldwide prevalence of about 0.2–1.4%.

Arthritis & Rheumatology 2016;68(12):2901–2910
18min read    
Education

This guideline replaces the earlier CG88 i.e. Early management of persistent non-specific low back pain.

NICE
10 min read    
Education

Fibromyalgia syndrome is a common disorder characterized by multiple tender points, widespread deep muscle pain, sleep disturbance, fatigue and depression.

14min read    
Education

Gout involves problem with the purine metabolism. In this disease, the uric acid levels are increased (hyperuricemia) and urate crystals accumulates in joints and tissues of the body.

NICE
6 min read    
Education

Syndesmotic injuries at the ankle joint are injuries to the ligaments that connect the tibia and fibula.

NICE
10 min read    
Education

Fibromyalgia is a syndrome which is indicated by chronic widespread pain.

ACSAP
10 min read    
August 19, 2017

Crescendo Bioscience, a wholly-owned subsidiary of Myriad Genetics, Inc., put forward the new data on the use of Vectra® Disease Activity (DA) test to predict treatment response in patients suffering from rheumatoid arthritis (RA). The report was published online in the journal Arthritis & Rheumatology.

Globe NewsWire
Key Take-Away:

 A 800 mg/day pharmaceutical-grade Chondroitin sulphate was found to be better than placebo and similar to celecoxib in alleviating pain and enhancing function in patients with symptomatic knee osteoarthritis (OA) over 6 months.

Osteoarthritis is one of the most common musculoskeletal disorders that significantly impact the quality of life of people suffering from it.  It is known to be a chief cause of pain, loss of funct

Ann Rheum Dis 2017; 0:1–7.
24min read    
Education

This guideline replaces the earlier CG88 i.e. Early management of persistent non-specific low back pain. Here, low back pain and sciatica has been estimated and managed in people aged 16 and over alongwith the physical, psychological, pharmacological and surgical treatments for the same. It is pivoted to improve people's quality of life, encouraging the most effective forms of care for low back pain and sciatica.

NICE
10 min read    
August 30, 2017 - September 1, 2017
Cork City , Ireland
1min read