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April 10, 2017

In the last decade, our understanding of the physiology of pain and pain pathways has expanded considerably and more effective pain-relieving medications are available these days. The present study focused to distinguish the efficacy and safety of intramuscularly administered nalbuphine, butorphanol and pentazocine (opioid agonist-antagonists ) for postoperative pain relief after abdominal hysterectomy.

International Journal of Basic & Clinical Pharmacology
8min read    
April 10, 2017

Ultrasound-guided subsartorial saphenous nerve block is frequently used to furnish the complete surgical anesthesia of the foot and ankle, alongwith with a popliteal sciatic nerve block. Nonetheless, the saphenous nerve is more strenuous to reliably block than the sciatic nerve in the popliteal fossa. This may be due to its small caliber and absence of a prominent vascular landmark in the subsartorial plane distal to the adductor canal. Since saphenous nerve is a sensory nerve only, neurostimulation can be used to induce a “tapping” sensation on the anteromedial aspect of the lower leg extending towards the medial malleolus.

Regional Anesthesia and Acute Pain
10min read    
April 10, 2017

Joint pain and stiffness along with the panful inflammation is common among patients suffering from rheumatoid arthritis (RA). Quintana-Duque et al.conduced a study to distinguish the levels of 25-hydroxyvitamin D (25(OH)D) in patients with early-onset rheumatoid arthritis (EORA) versus a healthy control group. Also, to assess the association of 25(OH)D deficiency and the BsmI polymorphism of the vitamin D receptor gene with clinical, radiological, and laboratory parameters.

JCR: Journal of Clinical Rheumatology
8min read    
April 10, 2017

Recent review conducted by researchers evaluated the relationship between rheumatoid arthritis (RA), a chronic inflammatory disease of the joints and periodontitis, a chronic inflammatory disease of the gums. It is known that RA is an inflammatory condition that can lead to tooth loss and other health complications.  This association between these conditions has been demonstrated previously as well, but remained contraversial. Therefore, the purpose of the presented meta-analysis was to comprehensively determine the association between RA and periodontitis.

The International journal of periodontics & restorative dentistry
7min read    
April 10, 2017

With aging, especially after menopause, women tend to have weaker bones that thinner and more brittle and thus likely to break easily. This condition is known as postmenopausal osteoporosis. The osteoporotic fractures are concerned with substantial morbidity and mortality in postmenopausal women, especially older women.

Gynecol Endocrinol.
7min read    

Occurrence of headache is very common nowadays, even in kids. Parents usually consider these headaches as a severe problem in kids. Physical examination by doctor is preferred, that help decide whether neuro-imaging is required or not. Mostly, based on the diagnostic reports, treatment of headache is initiated. 

16min read    

Ankylosing spondylitis (AS) is a chronic immune-mediated inflammatory disease with worldwide prevalence of about 0.2–1.4%.

Arthritis & Rheumatology 2016;68(12):2901–2910
18min read    

The initiation of recurrent methotrexate (MTX) and various biologic agents has had such an influence on the treatment of rheumatoid arthritis (RA) that a standard shift has appeared towards earlier

Ann Rheum Dis. 2016;75(11):19171923.
21min read    

Polycystic Ovarian Syndrome (PCOS) is one of the most common endocrinopathies in women of reproductive age, with incidences ranging between 4–20%.

PLOS ONE | DOI:10.1371/journal.pone.0162911
21min read    

The most usual form of inflammatory arthritis is gout. As per the recent guidelines, a xanthine oxidase inhibitor as urate-lowering therapy (ULT) must be recommended to bring serum uric acid (SUA) to the target range of < 6 mg/dL

The Journal of Rheumatology 2017; 44:3
19min read    
Education

Fibromyalgia syndrome is a common disorder characterized by multiple tender points, widespread deep muscle pain, sleep disturbance, fatigue and depression.

14min read    
Education

Gout involves problem with the purine metabolism. In this disease, the uric acid levels are increased (hyperuricemia) and urate crystals accumulates in joints and tissues of the body.

NICE
6 min read    
Education

Syndesmotic injuries at the ankle joint are injuries to the ligaments that connect the tibia and fibula.

NICE
10 min read    
Education

Fibromyalgia is a syndrome which is indicated by chronic widespread pain.

ACSAP
10 min read    
Education

This guideline is an updated version on the drug treatment options for post-shingles pain. It was based on the review of the recent litrature and the modified by the author.

The Shingles Support Society
3min read    
April 10, 2017

In the last decade, our understanding of the physiology of pain and pain pathways has expanded considerably and more effective pain-relieving medications are available these days. The present study focused to distinguish the efficacy and safety of intramuscularly administered nalbuphine, butorphanol and pentazocine (opioid agonist-antagonists ) for postoperative pain relief after abdominal hysterectomy.

International Journal of Basic & Clinical Pharmacology

Occurrence of headache is very common nowadays, even in kids. Parents usually consider these headaches as a severe problem in kids. Physical examination by doctor is preferred, that help decide whether neuro-imaging is required or not. Mostly, based on the diagnostic reports, treatment of headache is initiated. 

16min read    
Education

Fibromyalgia syndrome is a common disorder characterized by multiple tender points, widespread deep muscle pain, sleep disturbance, fatigue and depression. The cause and cure for fibromyalgia is unknown, but medications and other treatments can helps to reduce the symptoms. Although, people experience pain and tenderness all over the body, they are often diagnosed by the doctors based on the tender spots or points in certain places of the body.

What are tender points?

14min read