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According to a recent study published in "Annals of Rheumatic Diseases" Journal, Pharmaceutical-grade Chondroitin sulfate (800mg/day) was found to possess similar efficacy as celecoxib in managing Knee Osteoarthritis (OA).

7min read    

The results of the latest study demonstrated the effectiveness of Leflunomide (LEF) in arthritis patients with failed methotrexate response. The investigators found LEF to be devoid of serious adverse effects and it can be considered a reasonable and cost-effective treatment option before initiating biological therapy.

8min read    

The customizable thin insoles provided a significant reduction in pain produced by walking, confirms the recent study published in "Musculoskeletal care" Journal.

7min read    

A recent study published in "Arthritis Care and Research" revealed that the combination of ITGβ5, M2BP, and C-Reactive protein (CRP) level distinguishes psoriatic arthritis (PsA) from those with psoriasis without psoriatic arthritis (PsC). Also, the combination was found to be better than CRP level alone.

7min read    

“Patient navigators do not ameliorate oral DMARD adherence”, confirms latest study published in Arthritis Care & Research Journal

9min read    
Key Take-Away:

Effects of 5-HT on pain perception did not found to be confounded by mood changes.

Pain is an essential learning mechanism which is important for survival and avoiding damage. Pain processing is linked to various regions of brain that integrates information to form a pain matrix. It occurs due to combination of multiple factors such as stimulus intensity, emotional and contextual state and individual past experiences which contributes to the expectation of pain.

Martin et al. 5-HT modulation of pain perception in humans. Psychopharmacology (2017) 234:2929–2939
16min read    
Key Take-Away:

Radiological features are found to be importanat aspect in the decision of viscosupplementation in patients with hip osteoarthritis.

Osteoarthritis (OA) is a common articular disease that is highly prevalent in aging population and expected to grow from 11% in 2006 to 25% by 2030. The most frequent cause of lower limb OA is Hip OA (HOA) that significantly affects multiple aspects of quality of life. 

Eymard et al. BMC Musculoskeletal Disorders (2017) 18:3
17min read    
Key Take-Away:

There was no correlation found between changes in synovitis and the reduction in knee pain following brace wearing in patients with Patello-femoral Joint Osteoarthritis (PFJOA).

Patello-femoral Joint Osteoarthritis (PFJOA) refers to a condition that leads to knee pain in middle aged adults. A recent randomized controlled trial had showed that flexible sleeve knee brace in patients with symptomatic PFJOA had significant improvement in pain after 6 weeks and a reduction in bone marrow lesion (BML) volume in the PFJ. 

Swaminathan et al. BMC Musculoskeletal Disorders (2017) 18:347
14min read    
Key Take-Away:

Persistent post-traumatic headache and migraine are correlated  with differences in brain structure, suggesting differences in pathophysiology.

Many patients with post-traumatic headache (PTH) have characteristics that exhibits homogeneity with migraine phenotype. The only clinical feature that distinguishes PTH from migraine is the history of head injury. 

Schwedt et al. The Journal of Headache and Pain (2017) 18:87
15min read    
Key Take-Away:

Acupoint-stimulation  is an effective measure in relieving pain associated with primary dysmenorrhoea (PD) and also offers additional benefits in increasing the overall effectiveness.

Dysmennorhoea is a prevalent gynecological complaint among adolescent and young adult females. The global prevalence of the condition differs among various countries and ranges from 80% in Western Australia, to 60% in Canada, 48.4% in Mexico, and 79.9% in Iran. Among 50% of females of reproductive age with painful menstruation, 10% suffers from severe dysmenorrhoea. 

Xu et al. BMC Complementary and Alternative Medicine (2017) 17:436
16min read    
Education

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read    
Education

Chronic pain can be a serious consequence of surviving cancer. The prevalence of pain in cancer survivors has been reported to be as high as 40%.

American Society of Clinical Oncology
10 min read    
Education

Neuropathic pain is defined as the pain initiated or caused by a primary lesion, dysfunction, or transitory perturbation of peripheral or central nervous system.

Western Australian Therapeutic Advisory Group
2min read    
Education

Transitional care, as defined by the Society for Adolescent Medicine refers to the purposeful, planned movement of adolescents and young adults with chronic physical and medical conditions from chi

Ann Rheum Dis 2016;0:1–8
4min read    
Education

As per the World Health Organization (WHO), osteoporosis refers to a progressive systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of the bone tissues, w

Arch Osteoporos. 2017; 12(1): 43.
2min read    
June 5, 2018

According to a recent study published in "Annals of Rheumatic Diseases" Journal, Pharmaceutical-grade Chondroitin sulfate (800mg/day) was found to possess similar efficacy as celecoxib in managing Knee Osteoarthritis (OA).

Key Take-Away:

Effects of 5-HT on pain perception did not found to be confounded by mood changes.

Pain is an essential learning mechanism which is important for survival and avoiding damage.

Martin et al. 5-HT modulation of pain perception in humans. Psychopharmacology (2017) 234:2929–2939
16min read    
Education

Sinusitis affects about 1 in 8 adults in the United States, resulting in over 30 million annual diagnoses. Sinusitis is the fifth most common diagnosis in the world; more than 1 in 5 antibiotics prescribed in adults are for sinusitis. Irrespective of the high incidence and economic burden of sinusitis, significant practice dissimilarities exist through and within the numerous disciplines involved in managing the condition. The guideline is applicable for patients aged 18 years and above with a clinical diagnosis of uncomplicated rhinosinusitis.

American Academy of Otolaryngology-Head and Neck Surgery Foundation
15 min read